Volume Status Resources

Knowing volume status is key in critical care. The American College of Cardiology and American Heart Association recommend assessing volume status in all heart failure patients. Even small 10% increases in volume are directly linked to worse outcomes and longer hospital stays. A third of all ICU patients has an episode of volume resuscitation, and a quarter of all ICU patients suffer from AKI.

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mGFR Resources

In kidney disease, GFR is the primary indicator of injury, disease progression, and recovery. Currently, Serum Creatinine (SCr) is the most common clinical assay for estimating renal function (eGFR). This is a poor surrogate for true GFR (Glomerular Filtration Rate) as it is a trailing indicator by approximately 24-48 hours. Patients lose approximately 50% of their kidney function by the time the serum creatinine measures above normal. It is slow to reflect kidney impairment and recovery and is impacted by non-renal factors of age, diet, muscle mass, and hemodynamics.

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Clinical Need Resources

For more information on the clinical need for effective volume status and mGFR measurements, please explore the resources below.

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